Tetracycline HCl 2% topical solution

Tetracycline HCl 2%
topical solution




Materials:
Tetracycline HCl …………………………2.2 gm.
Alcohol 95 % …………………………….45 ml.
Isopropyl alcohol 99 % …………………..5 ml.
Citric acid ………………………………..100 mg.
Sodium bisulfite ………………………….100 mg.
Water to ………………………………….100 ml


Procedure


Dissolve tetracycline in the mixture of ethanol and isopropanol.
Dissolve the citric acid and the bisulfite in water.
Add the two solution together, mix well, and adjust the volume
References: 11, 33[1].


Comment:
A beyond-use date is 60 days at room temperatureThis formula is used for the treatment of acne vulgaris.Not recommended for use to children below 11 years.






Other formula
Tetracycline HCL................................. 220 mg,

Sodium bisulfite ………………………100 mg.
Ethanol 95% ………………………..…45 ml.
Citric acid ……………………………..100 mg.
Water qs ……………………………….100 ml.







[1] Int. Jor of pharmaceutical compounding vol. 7 No. 3 May/June 2003